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Washington University Experience | BASIC PROCESSES | Artifacts | Artifact - Freeze-Thaw | 1B5 Artifact, frozen half brain into formalin without thaw, Case 2) H&E 4

Close-up of parenchyma between ice-crystals appears to show eosinophilic neurons but not nuclear changes, a histologic appearance more closely resembling dark cell change than hypoxic/ischemic injury. (H&E)

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