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Washington University Experience | BASIC PROCESSES | CNS-PNS Junction | 4A4 Root entry zone (Obersteiner-Redlich zone, Case 4) Coll IV whole mount
Collagen IV immunoreactivity predominantly labels the spinal roots strongly with little involvement of the cord. This reflects that PNS Schwannian elements have a basement membrane and CNS oligodendroglia do not (Coll IV IHC)