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Washington University Experience | BASIC PROCESSES | Crooke's Hyaline Change | 2A1 Crooke's Hyaline change (Case 1) H&E 100X 2
Crooke's hyaline change is histologically distinctive with doughnut shaped patterns in pituitary basophils, displacing granules to the margin of the cell as well as to the perinuclear region (H&E).