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Washington University Experience | BASIC PROCESSES | Neuroaxonal dystrophy | 19F3 Neuroaxonal Dystrophy, gracile (Case 27) EM 007 - Copy
The osmiophilic material in this dystrophic axon is seen at several magnifications. The densities may be composed of aggregates of coated material surrounding tubulovesicular/synaptic vesicles (just a speculation) and resemble the ultrastructural appearance of the dense osmiophilic material composing the core of Rosenthal fibers (arrow, 27JC) which might react with antisera against heat shock or crystallins. (Electron micrographs)