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Washington University Experience | DEVELOPMENTAL MALFORMATIONS | Agyria & Pachygyria | 1B1 Pachygyria (Case 1) LFB-PAS whole mount
1B1-6 Microscopic examination of the pachygyric areas in Case #1 show a 4 layer cortex and additional associated columnar disorganization and heterotopic nodules. ---- Image #1B1 This section of the 4 layered cortex shows the myelinated layer (arrowhead) and the underlying fourth layer between the arrowhead and arrow. The arrow marks the junction between the fourth layer and the white matter (LFB-PAS).