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Washington University Experience | DEVELOPMENTAL MALFORMATIONS | Empty sella syndrome | 1D1 Empty Sella Syndrome (Case 1) Crooke's change H&E 3 copy.jpg
1D1-3 Close up images of the residual gland shows relatively normal appearing architecture of the pituitary adenohypophysis. Nonetheless, the patient's chronic prednisone treatment for her lung disease resulted in Crooke's hyaline change (arrow, 1D1).