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Washington University Experience | DEVELOPMENTAL MALFORMATIONS | Holoprosencephaly - Complex | 1A6 Holoprosencephaly & Dandy-Walker & Hypoxia (Case 1) 5
Coronal sections of the frontal pole cortex shows continuity of the frontal lobes across the midline (cingulosynapsis). Also note the "gray-white reversal" resulting in the pale cortex and dark white matter most typically seen in hypoxia/ischemia.
