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Washington University Experience | INFECTION | Protozoa | Ameba | 1B2 Acanthamoeba (Case 1) & AIDS H&E 20X
Lesions are characterized by a mixed inflammatory infiltrate and scattered amoeba trophozoites (arrow, H&E) surrounded by reactive astrocytosis and an infiltrate of lymphocytes, plasma cells, histiocytes, including epithelial forms (sometimes forming poorly structured granulomata), macrophages, and neutrophils.