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Washington University Experience | INFECTION | Viruses | PML (JC Virus) | PML - IRIS | 1A2 (Case 1) T1 without contrast slice 8 - Copy copy
1A2,3 T1-weighted MRI is hypointense in typical PML lesions (arrows) but does not typically enhance with contrast. PML-IRIS T1-weighted lesions maintain hypointensity in non-contrast images but often show enhancement, usually patchy as in this case (arrows, 1A3), with contrast administration.