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Washington University Experience | INFECTION | Viruses | PML (JC Virus) | PML - IRIS | 2G3 PML & IRIS (Case 2) N7 H&E 40X area A copy copy
In pontine lesions there are numbers of markedly enlarged astrocytes (arrowhead) as well as infected oligodendroglia (arrow). Lesions are demyelinative and degenerative, as evidenced by axonal spheroids (red arrowheads)