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Washington University Experience | METABOLIC | Kernicterus | 7A1 Kernicterus (Case 7) ION H&E 10.jpg

7A1 Kernicterus (Case 7) ION H&E 10.jpg
Case 7 No History ---- In many of these cases there is little described microscopic pathology, some of which may reflect loss of deposited intra-neuronal bilirubin pigment with processing or over the passage of time. In the case number 7 shown here we have a case of bilirubin encephalopathy particularly involving the inferior olivary nuclei. There is neuron loss and astrocytosis and an unusual granular perikaryal neuronal eosinophilia (arrow, 7A3). Is this a finding representing selective distinctive histopathology of kernicterus?



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