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Washington University Experience | MISCELLANEOUS | Familial erythrophagic lymphohistiocytosis | 3C2 HLH, Perforin1 mutation (Case 3) H&E 5AA
3C2-4 Higher magnification images show perivascular accumulation of mixed inflammatory cells including large histiocytes/macrophages but no erythrophagocytosis. One difference from most ADEM cases is the absence of perivascular pallor which is expected in demyelination (H&E)
