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Washington University Experience | MISCELLANEOUS | Familial erythrophagic lymphohistiocytosis | 3D2 HLH, Perforin1 mutation (Case 3) LFB-PAS 4X best
Same section as #3D1 stained for myelin with LFB-PAS. Although there is a rather diffuse loss of myelin in the center of the specimen, it does not seem to be composed of perivascular demyelinated elements (LFB-PAS) as might be expected in ADEM.