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Washington University Experience | MUSCLE | Atrophy, muscle cell, NOS | 16A2 Atrophy-hypertrophy (Case 16) 1

Microscopic examination of the left quadriceps muscle biopsy material shows striated muscle fibers with fatty infiltration, extensive fiber size variation, and multifocal lymphocytic vascular cuffing. The majority of fibers exhibit severe atrophy with a concordant increase in the number of syncytial knots and are found in large groups. Multi-layered cuffs of small, benign appearing lymphocytes are associated with multiple small vessels within the muscle but lack definitive angionecrosis. (H&E)

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