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Washington University Experience | MUSCLE | Autophagic myopathy | 11A2 HCG (Case 11) H&E 40X
H&E stained muscle shows many fibers, including those in atrophic groups, have internal cracks and/or vacuolated sarcoplasm, some with granular debris within vacuoles. Endomysial connective tissue ranges from normal to mildly increased among fascicles. Some of the fibers with vacuoles have very basophilic sarcoplasm. (H&E)
