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Washington University Experience | MUSCLE | Myopathies with Mitochondrial Pathology | 23A1 (Case 23) Muscle_001 - Copy

Case 23 History ---- The patient is a 5-month-old girl who presents with severe hypotonia of unknown etiology. Operative procedure: Right quadriceps biopsy. ---- 23A1-3 There is little mitochondrial pathology; however, there are enlarged forms associated with lipid droplets and one markedly enlarged, pleomorphic form with disorganized cristae associated lipid droplets and intracytoplasmic invagination. There is a mild increase in the number of mitochondria, some of which have abnormal morphology. There is abundant glycogen, some of which is membrane bound.

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