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Washington University Experience | MUSCLE | Myopathies with Mitochondrial Pathology | 33A2 (Case 33) EM046 - Copy

Individual mitochondria varied significantly in size and shape, some were branched and accumulated in small groups within the interior of the muscle fiber. In a few fibers inter-sarcomeric mitochondria were smaller than normal mitochondria and, in some regions, appeared to be absent entirely. In a subpopulation of fibers mitochondria contained paracrystalline “parking lots”, internal structure within long cylindrical forms and in cross sections. (electron micrographs)

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