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Washington University Experience | MUSCLE | Myopathies with Mitochondrial Pathology | 36A3 (Case 36) Cervical Paraspinal_018 - Copy

36A3 (Case 36) Cervical Paraspinal_018 - Copy
Paraspinous muscle: This muscle had a definitive ultrastructural phenotype characterized by significantly increased numbers of mitochondria, both in a subsarcolemmal distribution and deeper within the fiber in smaller clumps. Mitochondria were enlarged, had unusual lengths and angular shapes, varying from fiber to fiber, containing dark coarse cristae and numerous associated lipid droplets. (electron micrograph)


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