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Washington University Experience | MUSCLE | Myopathies with Mitochondrial Pathology | 4F5B Mitochondrial myopathy MNGIE (Case 4) EM 026 - Copy

Many mitochondria have peculiar shapes and focal vacuolation. (electron micrographs) ---- Not shown: With NADH, occasional fibers have increased staining and others have slightly irregular patterns of internal architecture. Sudan staining showed a number of these fibers have increased lipid with increased sized droplets. Comment : This was called mitochondrial myopathy consistent with a clinical diagnosis of Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE).

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