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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | Inflammatory Demyelination | 16I2 Inflammatory Demyelination (Case 16) Ki67 20X 3

16I2 Inflammatory Demyelination (Case 16) Ki67 20X 3
Ki67 only highlights inflammatory cells and the total proliferation rate is less than 1%. Not shown: CD138 highlights clusters of perivascular and intraparenchymal plasma cells. There is no evidence of IDH1 (R132H) mutated cells. GMS, PAS and AFB stains were performed and show no organisms. ---- Comment: The collective morphological and immunohistochemical features are consistent with an inflammatory demyelinating process.



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