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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | MS - Schwannian CNS remyelination | 3C6 MS (Case 3) N14 Schwann remyelination Coll IV whole mount 2

3C6 MS (Case 3) N14 Schwann remyelination Coll IV whole mount 2
This collagen IV stain demonstrates focused areas of reactivity involving the nodular areas. In this case the staining reflects presence of basement membrane surrounding Schwann cells and its absence in oligodendroglial myelin (collagen IV IHC).



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