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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | MS - Shadow Plaque | 2B3 MS Shadow & Cortical Plaque (Case 2) N1 LFB-PAS 1
The junction with the adjacent white matter appears to represent an active margin with complete loss of blue-stained myelin and increased cellularity (LFB-PAS) It is difficult in this image to appreciate preservation of histochemically-demonstrated myelin within the shadow plaque. Note the cellularity of the plaque. (LFB-PAS)