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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | MS - Tumefactive | 2D3 Tumefactive MS (Case 2) LFB-PAS 40X
Higher magnification image show loss of myelinated axons. Astrocytes have light blue cytoplasm and macrophages generally contain red granules of metabolized myelin. Macrophages are numerous in Virchow Robin spaces around the microvasculature.