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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | MS - Secondary Progressive (SPMS), fulminant | 1F7 MS, Secondary Progressive, fulminant (Case 1) CC2 NF Antigen 4 copy
Small stretches of axons are maintained but large numbers of neurofilament-laden macrophages and axonal swellings (arrows) attest to significant terminal axonopathy in this patient (NF IHC)