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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | MS - Secondary Progressive (SPMS), fulminant | 1P1 MS, Secondary Progressive, fulminant (Case 1) peri-dentate WM H&E 2

1P1 MS, Secondary Progressive, fulminant (Case 1) peri-dentate WM H&E 2
1P1,2 In the region of the dentate nucleus, the target for many of the Purkinje cells, there are numerous axonal spheroids possibly originating from Purkinje neurons which also show involvement of proximal axons (arrows, P2) (H&E)



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