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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | Sentinel & Steroid Rx Lesions | 2Q Sentinel Lesion (Case 2 - 2nd Bx) Bcl-6 2
Approximately 30% of large atypical cells show BCL-6 reactivity in a nuclear pattern (BCl-6 IHC) ---- These histomorphological and immunohistochemical findings are consistent with a diagnosis of diffuse large B-cell lymphoma of the CNS, GCB (germinal center B‐cell‐like phenotype).