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Washington University Experience | MYELIN (IMMUNE-MEDIATED) | Sentinel & Steroid Rx Lesions | 4B4 Lymphoma, B cell & sentinel (Case 4) demyelinated area H&E 1
The white matter is vacuolated with scattered areas of pallor and astrocytosis which is not the typical appearance of demyelination which is usually more pale (myelin stains pink on H&E) with fewer empty vacuoles.