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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Binswangers | 2C5 Binswanger's Dz (Case 2) N4 LFB-PAS 40X
One of the differential diagnoses for a destructive pattern with vasculopathy involving white matter is CADASIL, in which PAS positive particles accumulate in arteriolar media. In this case the PAS is fibrillary but not granular (LFB-PAS)