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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | 17F3 RVCL (Case 17) N7 20X
The degenerating descending corticospinal tract is pale with macrophages. The adjacent neurons in the pontine nuclei are uninvolved as might be expected in a tract degeneration secondary to white matter degeneration rostrally.