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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | 18C7 TREX1 Disease (Case 18) H&E N22 20X
Pallor, astrocytosis, vascular hyalinization and acellular microvasculature is noted in this white matter lesion. Small- to medium-sized vessels within the white matter show paucicellular hyalinized thickening with focal mild to significant edematous expansion of the Virchow-Robin spaces. (H&E)