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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | 18D4 TREX1 Disease (Case 18) H&E N23 20X
These lesions are marked by rarefaction and gliosis with scattered hemosiderin/hematoidin-laden macrophages. The vessel in the center of the lesion is hyalinized and exhibits dystrophic calcification.