1A2 Cerebroretinal Vasculopathy, CRV, RVCL, TREX, HERNS, Case 1 Surgical) H&E 5 | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | MYELIN (NON-IMMUNE MEDIATED)

Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | 1A2 Cerebroretinal Vasculopathy, CRV, RVCL, TREX, HERNS, Case 1 Surgical) H&E 5

Large areas of necrosis with damaged vessels, ranging from hyalinization, telangiectases, concentric proliferation of mural elements to frank fibrinoid necrosis is the dominant appearance of this specimen but these changes do not appear to represent a classical vasculitis. (H&E) ---- 1A2 Higher magnification of image #1A1 (H&E)

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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL, TREX1 Mutation) | 1A2 Cerebroretinal Vasculopathy, CRV, RVCL, TREX, HERNS, Case 1 Surgical) H&E 5