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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Canavan Dz | 1C1 Canavan's Dz (Case 1) LFB-PAS WM 4X
1C1,2 The whole mount of the optic nerves and chiasm in this patient shows prominent spongiform changes, seen at higher magnification in image #1C2. The optic nerve is not uniformly involved (arrow, 1C1). (LFB-PAS myelin stain).