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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Canavan Dz | 1C2 Canavan's Dz (Case 1) LFB-PAS 4X copy
The whole mount of the optic nerve seen at higher magnification in this patient shows prominent spongiform changes. The optic nerve is not uniformly involved (arrow). (LFB-PAS myelin stain)