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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Delayed Radionecrosis | 2A0 Case 2 History

2A0 Case 2 History
Case 2 History ---- This 64 year old man presented in July 1967 complaining of headaches and flashing lights (scintillating scotoma). Radiologic examination included a pneumoencephalogram, plain films and a carotid arteriogram. These studies were suggestive of a partly calcified, tumor in the splenium of the corpus callosum. The patient was thought to have a slow growing glioma, possibly an oligodendroglioma, and given a course of radiation therapy (6000 rads) without a prior tissue diagnosis in November of 1974. The patient was readmitted to Barnes Hospital in January of 1977 for evaluation of focal status epilepticus and soon became unarousable. The patient remained unresponsive thereafter. Terminally, the patient spiked a fever to 104oF and had a marked decrease in his blood pressure with diminished urine output. Chest X-ray revealed a left lower lobe infiltrate. The right optic disc was blurred and the pupils were slightly reactive to light and unequal. The extremities were flaccid and no reflexes could be obtained. The gag reflex was decreased. The patient was thought to have probable aspiration pneumonia and secondary septic shock. His condition deteriorated and he expired.



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