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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Metachromatic Leukodystrophy | 1D3 Metachromatic Leukodystrophy (Case 1) 1 LFB-PAS WM
1D3,4 Whole mount of the hippocampus stained for myelin (1D3, LFB-PAS) shows loss of deep white matter and U-fiber sparing. There is parallel loss of axons (1D4, Bielschowsky) in deeper white matter which also shows U-fiber sparing