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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Neuroaxonal Leukodystrophy | 2B1 Neuroaxonal Leukodystrophy (Case 2) 1 H&E whole mount

2B1-3 These three whole mounts show a process focused on the subcortical white matter; note relative U-fiber sparing. ---- The perivascular pallor seen in this H&E examination had previously suggested a diagnosis of “Binswanger’s Disease” (subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy, SAE).

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