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Washington University Experience | MYELIN (NON-IMMUNE MEDIATED) | Solvent vapor leukoencephalopathy | 1A4 Solvent Vaport Leukoencephalopathy (AANP 1995, Case 2) LFB-PAS 3
1A4,5 The perivascular cellular aggregates are monocyte/macrophage in origin with large PAS-reactive granules and very few typical foamy macrophages. Oligodendrocytes are significantly diminished in number in areas with myelin pallor. In most sites, perivascular cells are accompanied by rare lymphocytes (LFB-PAS)