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Washington University Experience | NEOPLASM (SELLAR) | Craniopharyngioma, adamantinomatous | 14C2 Cranio SP resection, no live tumor (Case 14) Trichrome 1.jpg
Other stains (not shown): A CD45 immunostain highlights the numerous lymphocytic cells scattered throughout the tissues. A beta catenin immunostain is positive only in a cytoplasmic distribution of the glial tissues and blood vessels. Of note, mutational analysis for the BRAF V600E was attempted, but was not performed due to the absence of obvious tumor. ---- Overall, the tissues show predominantly reactive changes with a component of wet keratin, but no viable tumor in the form of stratified squamoid epithelium or stellate reticulum is definitively identified.