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Washington University Experience | NEOPLASM (SELLAR) | Pituitary Adenoma - Pituitary Neuroendocrine Neoplasm | Corticotroph | 13A1 PA, ACTH, CR (Case 13) H&E 2 copy

Case 13 History ---- [57yo female with a 2-year history of progressive Cushing's symptoms including moon facies, blushing, easy bruising, and elevated blood sugars, who had a suspicious pituitary lesion on MRI.] ---- 13A1 A whole mount section of the pituitary show both neoplastic (arrowheads) and nonneoplastic tissue. The neoplastic tissue has monomorphic round nuclei and granular eosinophilic cytoplasm with well-defined cell borders but no evidence of Crooke’s hyaline change. A subpopulation of the non-neoplastic pituitary acini have both coarse basophilic cytoplasm as well as glassy eosinophilic cytoplasmic inclusions.

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