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Washington University Experience | NEOPLASM (SELLAR) | Pituitary Adenoma - Pituitary Neuroendocrine Neoplasm | Corticotroph | 8C2 PA CR (Case 8) CK 40X
Pan-cytokeratin (8C1,2) and CAM5.2 (8C3,4) show intense circumferential perinuclear staining in a subpopulation of tumor cells, confirming the presence of Crooke's hyaline in approximately 20% of the tumor cells. (CAM5.2 IHC)
