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Washington University Experience | NEOPLASMS (EMBRYONAL) | ATRT - Atypical Teratoid Rhabdoid Tumor | 2A1 AT-RT (Case 2) H&E 20X
Case 2 History ---- The patient was a 20 month old boy with a supratentorial, intraparenchymal tumor with contrast enhancement and calcification. Operative procedure: Resection. ---- 2A1-3 This is a high-grade neoplasm composed of sheets of large epithelioid cells, aggregates of primitive cells with scanty cytoplasm, and cords of highly atypical cells in a myxoid background. Most prominent are multiple aggregates of large cells with eccentric, vesicular nuclei, prominent nucleoli, and eosinophilic paranuclear inclusions. Numerous mitotic figures, apoptotic debris, and massive tumoral necrosis are noted.