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Washington University Experience | NEOPLASMS (EMBRYONAL) | ETMR - Embryonal Tumor Multilayered Rosettes | 2E4 ETANTR (Case 2) Plastic 2a copy

Multilayered rosette showing terminal bars (arrow). (One micron thick plastic embedded toluidine blue stained sections) ---- Not shown: Immunostains were performed and show nuclear retention of the INI-1 gene product (BAF 47). Neurofilament shows weak staining in the neuropil. The cells are negative for Neu-N. ---- FISH) studies show polysomies of chromosomes 2, 8, and 17. There was no evidence of: isochromosome 17, n-myc amplification, or c-myc amplification.

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