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Washington University Experience | NEOPLASMS (EMBRYONAL) | ETMR - Embryonal Tumor Multilayered Rosettes | 7A1 ETMR (Case 7) H&E 5

7A1 ETMR (Case 7) H&E 5
Case 7 History ---- The patient is a 1-year old boy with history of recurrent ETMR. The detailed history is not available. ---- 7A1-3 The tumor consists of an immature embryonal tumor featuring hyperchromatic crowded nuclei, conspicuous nucleoli, scant cytoplasm and high nuclear to cytoplasm ratio. The tumor cells are arranged in solid sheets, pseudo-papillary, multilayered and pseudostratified neuroepithelium with a central lumen that is frequently filled with eosinophilic material. There are frequent mitoses, although no significant tumor necrosis. Some degree of differentiation into mature neuropil is present. The adjacent cerebellar parenchyma is well demarcated from the tumor.



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