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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Classic Subtype | 12D Medulloblastoma (Case 12) BAF
INI1 is retained, ruling out an ATRT. ---- Not shown: FISH showed a gain of NF1 consistent with isochromosome 17q, a common abnormality in medulloblastomas. There was also polysomy of chromosomes 2 and 8. The histologic and immunophenotypic as well as the FISH results are that of a medulloblastoma, WHO grade IV.