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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Classic Subtype | 17A3 3Medulloblastoma, SHH type (Case 17) H&E 1
The tumor cells have small, oval, irregular, hyperchromatic nuclei with inconspicuous nucleoli, a high nuclear-to-cytoplasmic ratio, and scant cytoplasm. Mitotic activity is brisk. The tumor cells are seen infiltrating through the Virchow-Robin spaces in the adjacent fragments of cerebellum. There is no definitive area of nodular/desmoplastic differentiation.
