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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Classic Subtype | 18A Medulloblastoma (AFIP TS M9665 set Slide # 19, RES image) H&E whole mount

Case 18 History ---- [6yo male well until 5 months prior to admission when he developed nausea and projectile vomiting. A craniotomy was performed and a cerebellar vermis medulloblastoma was identified. Radiotherapy was performed post-operatively. One month prior to his second hospitalization tumor recurred in the suture line and cervical lymph nodes. At that time he walked with an unsteady gait, had a right internal strabismus and his pupils reacted sluggishly to light. There was a partial third nerve palsy and a partial contracture of the left leg. He was given radiation therapy to his neck but his condition steadily worsened with tonic convulsions lasting up to 5 minutes. He went rapidly downhill and expired. ---- At autopsy the spinal cord was involved by CSF spread of his medulloblastoma. (H&E)

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