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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Classic Subtype | 22A1 Medulloblastoma (Case 22) Nl Granule & Tumor H&E 1 copy

Case 22 History ---- [8yo female with a 4th ventricular tumor.] ---- 22A1,2 This is a small blue cell tumor composed of sheets of pleomorphic cells that have hyperchromatic nuclei, scant cytoplasm and high mitotic activity. In some sites Homer Wright rosettes are identified. The tumor cells (arrows) are admixed with normal cerebellum parenchymal granule neurons. In some cases, particularly during frozen section intraoperative analysis, it may be difficult to separate granule neurons from infiltrating medulloblastoma.

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