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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Classic Subtype | 4G Medulloblastoma (Case 4) Ki67.jpg
4G A Ki-67 immunostain demonstrates a variable but overall high index of proliferation, positive in approximately 30-40% of cells with areas of relatively minimal proliferation. ---- Not shown: An INI-1 stain is retained in tumor cell nuclei although there is a variably high cytoplasmic background. Likewise, p53 shows scattered nuclear reactivity.---- Overall, the histologic and immunohistochemical features are diagnostic of a medulloblastoma, classic type, WHO Grade IV
