Table of Contents

Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Extensive Nodularity (MBEN) | 1B3 Medulloblastoma, nodular (Case 1) H&E 4

The cells within the pale islands are generally homogeneous, with round nuclei, darkly speckled chromatin, a small basophilic nucleolus, and poor cellular demarcation, with cytoplasm forming a fine, fibrillary background. The cells within the streaming stromal phase generally have elongate, oval nuclei, usually separated by thin strands of collagen, but focally appear more primitive, with mildly irregular nuclear contours, and dense chromatin.

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